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The Weekly: The lesser-known breast cancer gene, Vitamin D for young-onset colorectal cancer, and more

August 20, 2021

The Weekly

Feature story

This Breast Cancer Gene Is Less Well Known, but Nearly as Dangerous

This Breast Cancer Gene Is Less Well Known, but Nearly as Dangerous

TUESDAY, August 17, 2021 (The New York Times)—For years, women with breast cancer in their families have been getting tested for mutations in two genes, known as BRCA1 and BRCA2, to determine whether they have a sharply elevated risk of the disease.

Now, doctors are increasingly recommending that anyone who was tested before 2014 go through genetic testing again — to look for a different mutation, one much less widely known.

It’s on a gene called PALB2, and people who have the mutation have almost as great a risk of getting breast cancer as those who have the BRCA mutations. Like the BRCA mutations, this mutation also increases a patient’s risk of ovarian and pancreatic cancer.

In other news…


Vitamin D Might Help Prevent Early-Onset Colon Cancer
August 18, U.S. News & World Report


Roche gets FDA approval for diagnostic tumour test
August 18, Reuters


Early-onset colorectal cancer may not be biologically different from average-onset disease
August 18, Healio


MMQB: Cancer Helped Ron Rivera Find His Voice, Including on the COVID-19 Vaccine
August 16, Sports Illustrated

Foundation news

Barbara Grassley, breast cancer survivor: “Just keep on getting checked!”

Barbara Grassley, breast cancer survivor: “Just keep on getting checked!”

Barbara Grassley, wife of Senator Chuck Grassley of Iowa, is a longtime breast cancer survivor and screening advocate. She is sharing her to story to encourage everyone to get their routine cancer screenings back on the books. Read more.

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